Study of the Expressions of level of sex hormones and their receptors for lung cancer patients
نویسندگان
چکیده
Most of lung cancer patients are with disorder expressions of estrogenic and androgen as well as their receptors ER and AR. In this study, a mechanism is proposed by testing Testosterone (T) and Estradiol (E2) levels and to look into the expressions of ER and AR for male non-small cell lung cancer patients to clarify the influence of sex hormones and their receptors. [Life Science Journal. 2009; 6(4): 78 – 86] (ISSN: 1097 – 8135).
منابع مشابه
Determination of Soluble HER-2/neu (sHER-2/neu) in Iranian Patients with Lung Cancer
Background: The HER-2/neu gene is located on chromosome 17q21 and encodes a 185-kDa transmembrane glycoprotein with tyrosine kinase activity reported to be released in soluble form in various malignancies. Objective: To evaluate the clinical significance of soluble Her-2/neu as a diagnostic marker in lung cancer. Methods: Serum levels of soluble HER-2/neu were measured in 43 patients with lung ...
متن کاملDifferent Gene Expressions of Alpha and Beta Glucocorticoid Receptors in Asthmatics
The response to glucocorticoids (GCs) therapy classifies severe refractory asthma (SRA) and mild asthma, so the glucocorticoid receptors (GCRs) gene expression may be involved in SRA pathogenesis. Thus, it is aimed to compare the expression levels of two GCR isoforms (GCRα and GCRβ) in SRA, mild asthmatics, and healthy controls. Total RNA was isolated from the peripheral blood mononuclear lymph...
متن کاملDifferent Gene Expressions of Alpha and Beta Glucocorticoid Receptors in Asthmatics
The response to glucocorticoids (GCs) therapy classifies severe refractory asthma (SRA) and mild asthma, so the glucocorticoid receptors (GCRs) gene expression may be involved in SRA pathogenesis. Thus, it is aimed to compare the expression levels of two GCR isoforms (GCRα and GCRβ) in SRA, mild asthmatics, and healthy controls. Total RNA was isolated from the peripheral blood mononuclear lymph...
متن کاملRelation between Estrogen and Progesterone Receptor Status with p53, Ki67 and Her-2 Markers in Patients with Breast Cancer
Background: Breast cancer is the most common cancer in women, containing approximately one third of all illnesses in women. Assessment of molecular markers is valuable in predicting the outcome of disease and decision making for optimal treatment. The purpose of this study was to determine the relationship between estrogen and progesterone receptors with Her-2, Ki67, P53, and clinicopathologica...
متن کاملLack of association between Estrogen and progesterone receptors and Oral Lichen Planus
Background: Lichen planus is a T-cell mediated autoimmune and chronic inflammatory disease that affects the skin and the mucous membrane. The results of numerous studies on oral mucosa have confirmed the effects of sex hormones on oral mucosa and the expression of estrogen (ER), progesterone (PR), and androgen receptors. Lichen planus is a common disease in middle-aged wo...
متن کامل